WALTHAM, Mass.--(BUSINESS WIRE)--AdnexusTM Therapeutics, Inc. today announced interim results of an ongoing Phase 1 open-label, dose-escalation study of its novel anti-angiogenic biologic, CT-322, in patients with advanced cancers. These results were presented at the 9th International Symposium on Anti-Angiogenic Agents in San Diego, CA by Anthony W. Tolcher, M.D., FRCP of the Institute for Drug Development Cancer Therapy and Research Center in San Antonio, Texas. CT-322 is a proprietary AdnectinTM protein therapeutic that, in preclinical studies, specifically binds to vascular endothelial growth factor receptor 2 (VEGFR-2), which regulates the primary tumor angiogenesis pathway. As a result, CT-322 blocks all known ligands for VEGFR-2.
