EurekAlert -- Comparative genomic hybridization (CGH) analysis provides comprehensive information about relative chromosomal losses and gains in malignant tumors in vitro. Using the CGH technique, chromosomal aberrations in both the primary tumor and its metastatic lymph nodes was detected in patients with esophageal squamous cell carcinoma (ESCC). Gains of 8q, 3q and 5p and the loss of 3p, 8p, 9q and 13q were specifically implicated in ESCC in the Linzhou population. Gains of 6p, 20p and the loss of 10pq may have contributed to the lymph metastasis of ESCC.
