The nutritional supplement glucosamine helps increase the pain-relieving power of ibuprofen, according to a Temple University study.This combination may let patients take lower doses of ibuoprofen to get the same amount of pain relief with fewer side effects.Glucosamine occurs naturally in the body. A synthetic version is used to treat osteoarthritis, a painful, degenerative joint disorder. While glucosamine is believed to prevent and repair bone and cartilage damage, it hasn’t yet been proven to block pain.