JERUSALEM--(BUSINESS WIRE)--Drug discovery and development is a highly risky process, with only one in 10,000 initial candidate compounds reaching the market. When taking into account the aborted candidates, the cost of developing one successful drug may even reach $1 billion, and the development process may take as long as 15-20 years. Therefore, integration of computational methods in the early stages of drug discovery has been one of the key trends in the pharmaceutical industry. Starting with high quality drug candidates should ultimately minimize clinical attrition rates and give rise to higher success rates.