Rembrandt, the 17th-century Dutch master known for his skill in using light to carry perspective, may have been wall-eyed, a U.S. researcher proposed on Wednesday. An analysis of 36 self-portraits of the great painter suggest he had a strabismus -- a misalignment of one eye that caused it to point slightly outward. This condition, popularly known as wall-eye, may have given Rembrandt van Rijn an advantage in translating three-dimensional scenes into two-dimensional paintings, said Margaret Livingstone, a Harvard Medical School neurobiologist.