Vitamin D Tests Are Inaccurate, Loyola University Chicago Stritch School of Medicine Study

Blood tests to measure vitamin D deficiency are among the most frequently ordered tests in medicine. But a Loyola University Chicago Stritch School of Medicine study of two new vitamin D tests found the kits are inaccurate in many cases. Earle W. Holmes, PhD, presented findings at ENDO 2012, the 94th Annual Meeting and Expo in Houston. Holmes and colleagues examined how well the two new tests, Abbott Architect and Siemans Centaur2, performed on 163 randomly selected blood samples. In 40 percent of the Abbott Architect specimens and 48 percent of the Siemans Centaur2 specimens, results were at least 25 percent too high or 25 percent too low. (The maximum recommended total allowable error is plus-or-minus 25 percent.)

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