This unique system for synthesising and analysing crystalline materials was designed in partnership between AstraZeneca and TTP LabTech. The overall objectives were to increase throughput, to explore experimental space efficiently and reliably and to automate the analysis of huge amounts of data. The project has been undertaken in stages, the first of which was a prototyping stage. This stage helped to minimise risk by tackling those design elements that carried the greatest number of unknowns early in the project. The next stage was the full design and build of a single screening machine to demonstrate control, functionality, and consistency of the basic automated polymorph screening processes. Now TTP LabTech has been asked to replicate the entire system in order to double the overall throughput.
Dr Philip Blenkinsop, MD TTP LabTech commented: ‘This has been a very challenging project for TTP LabTech requiring a number of novel solutions to be developed from both a hardware and software perspective. The completion of the first system is a real milestone and we look forward to delivering the next system with the next year.’
The AstraZeneca Project Manager, Matti Ahlqvist commented, ‘Working in partnership with TTP LabTech has resulted in an excellent solution. We set a very demanding specification and are delighted that virtually all the functionality has been achieved. Now that the first system is up and running for our drug projects, we look forward to delivery of the second system and further increasing throughput.’
About AstraZeneca
AstraZeneca is a major international healthcare business engaged in research, development, manufacturing and marketing of prescription pharmaceuticals and supplier for healthcare services. AstraZeneca is one of the world's leading pharmaceutical companies with healthcare sales of US $29.55 billion and is a leader in gastrointestinal, cardiovascular, neuroscience, respiratory, oncology and infection product sales. AstraZeneca is listed in the Dow Jones Sustainability Index (Global) as well as the FTSE4Good Index
For more information visit: www.astrazeneca.com
About TTP LabTech Ltd
Based near Cambridge, UK, TTP LabTech Ltd is a leading provider of development services to the international life science community. TTP LabTech’s development teams combine skills in chemistry, biology, and engineering to provide systems, products, and processes which are both innovative and practical. With offices in the UK, North America, and China the company is able to manage and support custom development projects for client companies in virtually all parts of the world.
For more information visit: www.ttplabtech.com/custom-solutions/index.html
