Below are Top 10 pharmaceutical companies based on market capitalization at the end of the second quarter 2012, and the year-ago quarter, calculated by multiplying the number of outstanding shares by the share price. U.S. companies generally report their numbers of outstanding shares in their 10-Q quarterly earnings filings with the Securities & Exchange Commission. Companies based outside the U.S. either disclose market cap directly, or their numbers of shares “in issue” or “in free issue” in half-year and full-year results disclosures. For all companies, closing share prices as of the dates of their outstanding-shares figures can be found through any of several free stock information websites. Figures of non-U.S. companies were converted from various currencies.#10 AstraZeneca
2012 Market Cap: $56.34 billion (6/30: 1.259 million shares * 6/29 price $44.75)
2011 Market Cap: $68.40 billion (6/30: 1.366 million shares * 6/30 price $50.07)
% Change: -17.6%
