LEUVEN, Belgium, May 13, 2016 /PRNewswire/ --
Developing Novel Medicines Targeting Diabetic Eye Disease
Highlights
ThromboGenics is focused on developing novel medicines for the treatment of diabetic eye disease
ThromboGenics presented its new drug development pipeline with 4 compounds, targeting novel treatments for diabetic retinopathy (DR) - non-proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR), in the presence or absence of diabetic macular edema (DME)
ThromboGenics initiated a Phase IIa clinical study (CIRCLE) evaluating THR-409 (ocriplasmin) to induce a complete posterior vitreous detachment (PVD), to prevent patients with non-proliferative diabetic retinopathy from progressing to proliferative diabetic retinopathy, a serious sight threatening condition
ThromboGenics signed a global and exclusive license agreement with Galapagos to develop and commercialize integrin antagonists for the treatment of diabetic eye disease. The Company has started to explore the potential of these compounds for the treatment of NPDR and PDR
Full report of OASIS 2 year follow up study with JETREA® (ocriplasmin) for the treatment of symptomatic VMA/VMT and Macular Hole (n=220) has been submitted and accepted for publication in a prestigious peer reviewed ophthalmology journal
15 ocriplasmin-related posters and presentations, with new research findings, were presented at the Association for Research in Vision and Ophthalmology (ARVO) 2016 annual meeting in Seattle
Following a collaboration agreement with the US-based NMTRC (Neuroblastoma and Medulloblastoma Translational Research Center), ThromboGenics' subsidiary, Oncurious, has initiated a Phase I/IIa study with TB-403 for the treatment of medulloblastoma, the most common pediatric malignant brain tumor
Cash and investments were €96.9 million as of the end of March 2016, compared with €101.4 million at the end of December 2015
ThromboGenics NV (Euronext Brussels: THR), a biotechnology company focused on developing novel medicines for diabetic eye disease, today issues a business update for the three month period ending 31 March, 2016.
ThromboGenics is focused on developing novel medicines for diabetic eye disease, particularly diabetic retinopathy (DR) and diabetic macular edema (DME).
Over the last two years, ThromboGenics has developed an attractive pipeline of disease modifying drug candidates. The pipeline consists of THR-409, THR-317, both from its in-house research, as well as THR-149 which resulted from a research collaboration with Bicycle Therapeutics, and THR-687, which was recently in-licensed from Galapagos NV.
Developing Novel Medicines Targeting Diabetic Eye Disease
Highlights
ThromboGenics is focused on developing novel medicines for the treatment of diabetic eye disease
ThromboGenics presented its new drug development pipeline with 4 compounds, targeting novel treatments for diabetic retinopathy (DR) - non-proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR), in the presence or absence of diabetic macular edema (DME)
ThromboGenics initiated a Phase IIa clinical study (CIRCLE) evaluating THR-409 (ocriplasmin) to induce a complete posterior vitreous detachment (PVD), to prevent patients with non-proliferative diabetic retinopathy from progressing to proliferative diabetic retinopathy, a serious sight threatening condition
ThromboGenics signed a global and exclusive license agreement with Galapagos to develop and commercialize integrin antagonists for the treatment of diabetic eye disease. The Company has started to explore the potential of these compounds for the treatment of NPDR and PDR
Full report of OASIS 2 year follow up study with JETREA® (ocriplasmin) for the treatment of symptomatic VMA/VMT and Macular Hole (n=220) has been submitted and accepted for publication in a prestigious peer reviewed ophthalmology journal
15 ocriplasmin-related posters and presentations, with new research findings, were presented at the Association for Research in Vision and Ophthalmology (ARVO) 2016 annual meeting in Seattle
Following a collaboration agreement with the US-based NMTRC (Neuroblastoma and Medulloblastoma Translational Research Center), ThromboGenics' subsidiary, Oncurious, has initiated a Phase I/IIa study with TB-403 for the treatment of medulloblastoma, the most common pediatric malignant brain tumor
Cash and investments were €96.9 million as of the end of March 2016, compared with €101.4 million at the end of December 2015
ThromboGenics NV (Euronext Brussels: THR), a biotechnology company focused on developing novel medicines for diabetic eye disease, today issues a business update for the three month period ending 31 March, 2016.
ThromboGenics is focused on developing novel medicines for diabetic eye disease, particularly diabetic retinopathy (DR) and diabetic macular edema (DME).
Over the last two years, ThromboGenics has developed an attractive pipeline of disease modifying drug candidates. The pipeline consists of THR-409, THR-317, both from its in-house research, as well as THR-149 which resulted from a research collaboration with Bicycle Therapeutics, and THR-687, which was recently in-licensed from Galapagos NV.
