Three variations of a human gene appear to impact human tuberculosis susceptibility, providing insight into why some patients infected with the Mycobacterium tuberculosis pathogen develop the full-blown disease and others do not. The finding is published in the online early edition of the Proceedings of the National Academy of Sciences (PNAS) for the week of June 19-23. The paper additionally describes how the association of two of the gene variants with the disease has been replicated.
