An analysis of almost 4,000 patients with breast cancer found that testing for high activity in a particular gene called alpha beta (aB)-crystallin could pick out women who were at greater risk of developing secondary brain tumors compared to women who tested negative.
A team including scientists at The Institute of Cancer Research, London, found that women whose breast cancer had begun to spread and who tested positive in the aB-crystallin test were three times more likely to have disease that spread to the brain than those who tested negative.
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