RESEARCH TRIANGLE PARK, N.C.--(BUSINESS WIRE)--In the largest trial ever reported in CIDP (chronic inflammatory demyelinating polyradiculoneuropathy), Gamunex® (Immune Globulin Intravenous [Human], 10% Caprylate/Chromatography Purified) was shown to reduce functional disability, while also demonstrating a prolonged time to relapse and a decreased probability of relapse longer-term (up to one year). The primary endpoint, response in functional disability, was observed in 54 percent of subjects treated with Gamunex (2g/kg loading dose, followed by 1g/kg maintenance dose every three weeks) compared to 21 percent on placebo when assessed up to six months in the first treatment period. Longer-term (up to one year), the probability of relapse was lower with Gamunex compared to placebo, 13 percent versus 45 percent, respectively. The use of Gamunex in the treatment of CIDP is investigational and has not been approved by the FDA.
