Smith & Nephew plc Announces-Holding(s) in Company

London, UK--(Marketwire - March 13, 2009) -

 NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Name of company Smith & Nephew plc 2. Name of shareholder having a major interest Prudential plc 3. Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of that person’s spouse or children under the age of 18 Non-beneficial 4. Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them Prudential Plc 5. Number of shares / amount of stock acquired 6. Percentage of issued class 7. Number of shares / amount of stock disposed 8. Percentage of issued class 9. Class of security Ordinary shares of US 20 cents 10. Date of transaction 11.03.09 11. Date company informed 12.03.09 12. Total holding following this notification Less than 3% 13. Total percentage holding of issued class following this notification Less than 3% 14. Any additional information No longer have a notifiable interest 15. Name of contact and telephone number for queries Gemma Parsons - Assistant Company Secretary 020 7960 2228 16. Name and signature of authorised company official responsible for making this notification Gemma Parsons - Assistant Company Secretary Date of notification 13.03.09 The FSA does not give any express or implied warranty as to the accuracy of this document or material and does not accept any liability for error or omission. The FSA is not liable for any damages (including, without limitation, damages for loss of business or loss of profits) arising in contract, tort or otherwise from the use of or inability to use this document, or any material contained in it, or from any action or decision taken as a result of using this document or any such material. This information is provided by RNS The company news service from the London Stock Exchange END