Signet Laboratories, Inc. Announces Availability Of Two New Monoclonal Antibodies

DEDHAM, Mass., March 16 /PRNewswire/ -- Signet Laboratories, Inc., a leading medical diagnostics/research company specializing in the development of monoclonal antibodies and diagnostic assays for cancer, infectious disease, and neurodegenerative disease, today announced the availability of two new monoclonal antibodies, EGFR, clone F4 and VEGF, clone VG-1.

EGFR, clone F4, has been implicated in the development and progression of a number of human solid tumors including lung, breast, prostate, colon, ovary, head, and neck.

VEGF, clone VG-1, is a secreted glycoprotein that is a potent and specific mitogen for vascular endothelial cells that stimulates angiogenesis during embryonic development and tumor formation.

Signet’s EGFR and VEGF antibodies offer researchers a valuable tool for cancer research. These antibodies complement Signet’s current product portfolio which includes markers such as D2-40, Cyclin D1, Cyclin E, HE4, and Hepsin.

About Signet Laboratories, Inc.

Signet Laboratories, Inc. (Signet, Dedham, MA) is a leading medical diagnostics/research company specializing in the development of monoclonal antibodies and diagnostic assays for cancer, infectious disease, and neurodegenerative disease. Signet was created in 1989 as a commercial spinout of Johnson & Johnson’s Cambridge Research Laboratories, Inc. (CRL, Cambridge, MA).

The Company was founded to continue the mission originally established at CRL -- the early detection and recurrence monitoring of patients with cancer and infectious disease. Signet has developed patented technology for diagnosis and recurrence monitoring and for risk assessment of asymptomatic patients in these areas. For more than a decade, the Company has aggressively maintained licensing and development programs, which are responsible for its broad patent and intellectual estate.

Contact Information Company Contact Immunohistochemistry Contact Colleen Scott Angela Thomas Signet Laboratories, Inc. Signet Laboratories, Inc. 180 Rustcraft Road 180 Rustcraft Road Dedham, MA 02026 Dedham, MA 02026 Phone: 781.915.1404 Phone: 781.915.1417 Fax: 781.461.2456 Fax: 781.461.2456 cscott@signetlabs.comathomas@signetlabs.com

Signet Laboratories, Inc.

CONTACT: Company Contact: Colleen Scott, Phone: +1-781-915-1404, Fax:+1-781-461-2456, cscott@signetlabs.com , or Immunohistochemistry Contact:Angela Thomas, Phone: +1-781-915-1417, Fax: +1-781-461-2456,athomas@signetlabs.com , both of Signet Laboratories, Inc.

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