Sigma-Aldrich Corporation Launches SpyLine(TM) Poly A+ Capture Kit

ST. LOUIS, Jan. 19 /PRNewswire-FirstCall/ -- Sigma-Aldrich , a leading Life Science and High Technology company, is pleased to introduce the SpyLine Poly A+ Capture Kit (product codes: SPY1 and SPY4). SpyLine is the newest addition to Sigma’s RNA product offerings and is an excellent tool for rapidly identifying the knockdown of gene expression for functional profiling of biological processes.

“The SpyLine Poly A+ Capture Kit simplifies knockdown measurements and gene expression analysis by allowing capture and amplification of mRNA in a single plate,” said Keith Jolliff, Strategic Marketing Director at Sigma- Aldrich. “We are very excited about the sensitivity and reproducibility of the kit, making it an excellent addition to our RNA product offering.”

The kit features the SpyLine Poly A+ Capture Plate, a 96-well PCR plate coated with oligo(dT) for selective capture of poly A+ mRNA from crude mammalian cell lysates. Reagents can be added directly to this capture plate for subsequent RT-PCR or real-time quantitative RT-PCR cycling and analysis. In addition, the 96-well format is suitable for automation. High throughput protocols are available for the Biomek(R) FX Workstation.

Learn more about SpyLine at http://www.sigmaaldrich.com/spyline , or visit us at Lab Automation 2006, January 22-24, in Palm Springs, California, USA.

Sigma-Aldrich is a leading Life Science and High Technology company. Our biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. We have customers in life science companies, university and government institutions, hospitals and industry. More than one million scientists and technologists use our products. Sigma-Aldrich operates in 35 countries and has 6,800 employees providing excellent service worldwide. We are committed to accelerating the success of our customers through leadership in life science, high technology and service. For more information about Sigma-Aldrich, please visit our award-winning website at sigma-aldrich.com.

This release contains forward-looking statements relating to future performance, goals, strategic actions and initiatives and similar intentions and beliefs and other statements regarding the Company’s expectations, goals, beliefs, intentions and the like, which involve assumptions regarding Company operations and conditions in the markets that the Company services. The Company does not undertake any obligation to update these forward-looking statements.

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CONTACT: Aimee Keithly of Sigma-Aldrich, +1-314-301-2036

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