Shire plc: Director/PDMR Shareholding - Feb. 15, 2018

Notification of transactions by person discharging managerial responsibilities.

February 15, 2018 - Shire Plc (LSE: SHP, NASDAQ: SHPG) (the “Company”)

Notification of transactions by person discharging managerial responsibilities

1. Details of the person discharging managerial responsibilities (“PDMR”) / person closely associated them (“PCA”)
a) Name Flemming Ornskov, MD, MPH
2. Reason for the notification
a) Position / status Chief Executive Officer - PDMR
b) Initial notification / amendment Initial notification
3. Details of the issuer, emission allowance participant, auction platform, auctioneer or auction monitor
a) Name Shire plc
b) LEI 54930005LQRLI2UXRQ59
4. Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a) Description of the financial instrument, type of instrument

Shire plc American Depositary Shares (“ADSs”)

Identification code ISIN: US82481R1068
b) Nature of the transaction

Release of ADSs awarded under the Shire Executive Annual Incentive on February 13, 2015. In accordance with the relevant plan rules, upon release the number of ADSs to be delivered was increased by an amount equivalent to the value of dividends paid by the Company in respect of the ADSs from the award date to the date of release.

(Details of related disposals of ADSs are referenced in section 5. below.)

c) Price(s) and volume(s) Price(s) Volume(s)
$0 2,546
d)

Aggregated information

- Aggregated volume

- Price

N/A (single transaction)
e) Date of the transaction February 13, 2018
f) Place of the transaction N/A
5. Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a) Description of the financial instrument, type of instrument

Shire plc American Depositary Shares (“ADSs”)

Identification code ISIN: US82481R1068
b) Nature of the transaction Automated disposal of ADSs in relation to the release of ADSs referenced in section 4. above. The proceeds of this disposal were used to satisfy personal tax liabilities arising from the release of the ADSs.
c) Price(s) and volume(s) Price(s) Volume(s)
See appendix below
d)

Aggregated information

- Aggregated volume

- Price

Weighted average price Aggregate volume

$132.0104

1,572

e) Date of the transaction February 13, 2018
f) Place of the transaction ARCX / CDRG / CROS / DBAX / EBXL / INET / NITE / NQPX

Appendix

Place of the transaction Aggregate volume Weighted average price
ARCX 369 $132.1072
CDRG 200 $131.9800
CROS 200 $131.9800
DBAX 100 $131.9900
EBXL 100 $131.9850
INET 203 $131.9716
NITE 300 $131.9800
NQPX 100 $131.9900
Total 1,572 $132.0104

Oliver Strawbridge
Senior Assistant Company Secretary

For further information please contact:

Investor Relations
Christoph Brackmann christoph.brackmann@shire.com +41 795 432 359
Robert Coates rcoates@shire.com +44 203 549 0874
Sun Kim sun.kim@shire.com +1 617 588 8175
Media
Lisa Adler lisa.adler@shire.com +1 617 588 8607
Katie Joyce kjoyce@shire.com +1 781 482 2779

NOTES TO EDITORS

About Shire

Shire is the global leader in serving patients with rare diseases. We strive to develop best-in-class therapies across a core of rare disease areas including hematology, immunology, genetic diseases, neuroscience, and internal medicine with growing therapeutic areas in ophthalmics and oncology. Our diversified capabilities enable us to reach patients in more than 100 countries who are struggling to live their lives to the fullest.

We feel a strong sense of urgency to address unmet medical needs and work tirelessly to improve people’s lives with medicines that have a meaningful impact on patients and all who support them on their journey.

www.shire.com

MORE ON THIS TOPIC