Medical News Today -- The researchers characterize their new technique as a neat solution to the “needle in a haystack” problem of nanoscale microscopy, but it’s more like the difference between finding the coffee table in a darkened room either by walking around until you fall over it, or using a flashlight. In a new paper,* a group from JILA - a joint venture of the National Institute of Standards and Technology (NIST) and the University of Colorado - finds tiny assemblies of biomolecules for subsequent detailed imaging by combining precision laser optics with atomic force microscopy.