Roche has been requested to provide additional clinical data on its skin cancer therapy Zelboraf to support a potential recommendation of the drug by the National Institute for Health and Clinical Excellence (NICE). The UK regulator has asked the company to make further information available that demonstrates the benefits of Zelboraf for the treatment of unresectable locally advanced or metastatic BRAF V600 mutation-positive melanoma. Key to this process will be Roche’s ability to prove that the drug is a cost-effective means of treating this form of cancer, and offers enough long-term benefits to be worth funding via the NHS.
