Release of Novagen, Inc. KOD Xtreme(TM) Hot Start DNA Polymerase

May 14, 2008 – To address the needs of scientists working with challenging PCR targets, EMD (in partnership with Toyobo Co.) announces the release of the Novagen® brand KOD Xtreme™ Hot Start DNA Polymerase kit (not available in Japan). KOD Xtreme polymerase is an optimized PCR system for the amplification of long or GC-rich DNA templates.

The system includes an ultra high-fidelity KOD DNA polymerase complexed with two monoclonal antibodies to permit hot start thermocycling, along with specially formulated 2X buffer. KOD Xtreme polymerase enables convenient ambient-temperature setup compatible with automation, while eliminating mispriming and primer-dimer formation.

The system quickly and accurately amplifies genomic and phage or plasmid DNA targets up to 24 and 40 kb in length, respectively. It successfully amplifies challenging DNA templates with up to 90% GC content. Each kit provides 200 U KOD Xtreme Hot Start DNA Polymerase, an optimized buffer and dNTPs sufficient for 200 amplification reactions. The polymerase produces blunt-ended DNA products suitable for cloning with the Novagen Perfectly Blunt® and (following treatment with T4 polymerase) LIC Vector Kits. For more information, see: www.novagen.com/kod

Robyn Perrin, Ph.D. Technical Writer, Global Marketing Communications Phone: 608-442-4009 Fax: 608-238-1388 Email: robyn.perrin@emdchemicals.com

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