TAE Life Sciences (TLS), a biological-targeting radiation therapy company developing next-generation boron neutron capture therapy solutions (BNCT) for hard-to-treat cancers, has announced an agreement with RaySearch Laboratories for Raystation support of the TLS Alphabeam™ System.
| FOOTHILL RANCH, Calif., July 16, 2020 /PRNewswire/ -- TAE Life Sciences (TLS), a biological-targeting radiation therapy company developing next-generation boron neutron capture therapy solutions (BNCT) for hard-to-treat cancers, has announced an agreement with RaySearch Laboratories for Raystation support of the TLS Alphabeam™ System. The Alphabeam System is a highly targeted, efficient treatment program, treating patients in fewer sessions, without the typical side effects of radiation treatments. Raystation provides support for BNCT through optimized treatment plan creation and dosage. Under the terms of the agreement, RayStation will work in conjunction with TAE Life Sciences’ proprietary dose calculation software, which can be installed in a clinical environment and configured in a single or multi-room BNCT center. Treatment planning system RayStation supports BNCT treatment with tools enabling contouring, image importing, reporting, plan creation and evaluation, as well as support for defining BNCT-specific models for the relative biological effectiveness. Unlike conventional radiotherapy and even more advanced particle therapy such as the proton and carbon ion, BNCT is a combination treatment that uses the biological targeting precision of boron-10, which acts as a homing beacon and the activation by a neutron source. When the boron-containing cells are irradiated by epithermal neutrons, the combination releases a highly localized therapeutic dose that destroys cancer on a cell-by-cell basis with minimal damage to healthy tissues. BNCT minimizes the need for physical targeting accuracy and complex tumor motion management procedures. Instead, the therapy targets cancer cells biologically by the boron-carrying drugs that preferentially target tumor tissue as well as undetected microscopic cancer cells. Importantly, during a time when the clinic and hospital space is at a premium, the increased accuracy offered by biological targeting means that BNCT requires only one or two treatments. Conventional radiotherapy requires fractionated treatments to offset side effects. Bruce Bauer, CEO, TAE Life Sciences, says: “The new era of accelerator-based BNCT offers a highly promising therapy for hard-to-treat cancers, both in effectiveness and reduced treatment time. We are excited to partner with RaySearch in the integration of RayStation-NCT with our compact AlphaBeam system. Our partnership will help accelerate the commercialization of hospital-based BNCT and greatly benefit clinicians and cancer patients globally.” Johan Löf, founder and CEO, RaySearch, says: “BNCT is gaining ground as an option for certain types of tumor and we are keen to support partner companies operating in this field of radiation therapy. I am pleased to share the news of our partnership with TAE Life Sciences to advance cancer treatment.” TLS recently announced a $30M Initial B Round Phase funding, which will speed the development of novel proprietary boron-10 target drugs at the same time that it hones its neutron beam accelerator technology for BNCT. TLS is the only company to focus on the parallel development of new boron-10 drugs and a neutron accelerator system, a combination aimed at difficult-to-treat cancers. About TAE Life Sciences About RaySearch About RayStation The drugs and machine being developed by TAE Life Sciences is currently for investigational use only and has not been approved for sale or commercial use.
SOURCE TAE Life Sciences |
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