Purigen Launches Ionic® Cells to Pure DNA Kit for White Blood Cell and Peripheral Blood Mononuclear Cell Control Samples

PLEASANTON, Calif.--(BUSINESS WIRE)-- Purigen Biosystems, Inc., a leading provider of next-generation technologies for extracting and purifying nucleic acids from biological samples, today announced the launch of the Ionic Cells to Pure DNA Kit. The new kit has been optimized to allow users of the Ionic® Purification System to extract increased yields of high-quality DNA from white blood cells (WBCs), peripheral blood mononuclear cells (PBMCs), and cultured or sorted cells.

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The Ionic® Cells to Pure DNA Kit from Purigen Biosystems allows users of the Ionic® Purification System to extract increased yields of high-quality DNA from white blood cells, peripheral blood mononuclear cells, and cultured or sorted cells. (Graphic: Business Wire)

The new Ionic Cells to Pure DNA Kit was developed to support Purigen’s existing customers who perform work with FFPE tumor tissue and use blood cells as a control, though it can be used for a broad array of applications. The kit supports the extraction of high yields of DNA from samples containing 50,000 to 5 million cells and produces consistently higher DNA concentrations than traditional technologies. This workflow minimizes the need for sample concentration prior to downstream analysis techniques such as next-generation sequencing. The Ionic Cells to Pure DNA Kit can also be used to analyze immune cells, archive DNA for biobanks, and enable molecular profiling of cultured and FACS sorted cells.

“We are excited to offer the new Ionic Cells to Pure DNA Kit, which was developed based on direct feedback from our customers,” said Chris Grimley, Senior Vice President of Sales and Marketing for Purigen. “This kit extends the workflow and performance advantages of the Ionic Purification System to cells, enabling scientists to expand their use of Ionic beyond FFPE tissue and perform comparison studies with normal WBC or PBMC control samples, all on a single platform.”

The Ionic Cells to Pure DNA Kit utilizes Purigen’s Ionic Purification System, a benchtop instrument that allows for the automated extraction of pure and abundant nucleic acids from a wide range of sample types, including fresh, frozen, and FFPE tissue. These biological samples are gently lysed and loaded into an Ionic® Fluidic Chip. The Ionic System uses the company’s innovative isotachophoresis (ITP) technology to apply an electric field to the chip, which isolates nucleic acids in their native form. Since the nucleic acids are not denatured or dehydrated, nor are they bound and stripped from fixed surfaces, the process minimizes fragmentation and eliminates bead or buffer contamination.

The Ionic Cells to Pure DNA Kit consists of six chips and a reagent set with all necessary enzymes and buffers to perform DNA extraction from 48 samples. The kit is available now through Purigen’s direct sales channels. For more information, please visit https://www.purigenbio.com/applications/ionic-cells-pure-dna.

About Purigen Biosystems

Purigen Biosystems is redefining nucleic acid sample preparation with an innovative platform based on the highly efficient isotachophoresis technology invented by Juan Santiago, PhD, and his team at Stanford University. Purigen’s automated benchtop instrument and accompanying microfluidic chip purify nucleic acid samples from a wide variety of sources, including minute or otherwise challenging cancer samples. The purified nucleic acids are immediately compatible with a wide range of downstream detection methods, including next-generation sequencing, PCR, and other genomic tests. For more information, visit www.purigenbio.com.

Ionic is a registered trademark of Purigen Biosystems, Inc. All other trademarks are the property of their respective owners. All products described herein are intended FOR RESEARCH USE ONLY and NOT FOR USE IN DIAGNOSTIC PROCEDURES.

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