SOUTH SAN FRANCISCO, Calif., Aug. 24 /PRNewswire/ -- Portola Pharmaceuticals, Inc. today announced two oral presentations at the European Society of Cardiology (ESC) Congress 2009 in Barcelona, Spain, that will feature its investigational antiplatelet drug elinogrel, a P2Y12 ADP receptor antagonist that is currently in Phase II clinical development with Novartis, Portola’s development and commercialization partner.
Title: First in Patient Experience with a New, Direct Acting, Reversible P2Y12 Inhibitor, Elinogrel (PRT060128): Evaluation in Patients with High Platelet Reactivity During Clopidogrel Therapy (Program #2678)
Presenter: Paul A. Gurbel, M.D., Director, Sinai Center for Thrombosis Research, Baltimore, Md.
Date: Monday, August 31, 4:45-5:00 p.m.
Location: Sofia Room, Zone 1
About Elinogrel
Elinogrel is the only direct acting, reversible, i.v. and oral P2Y12 ADP receptor antagonist in clinical development. Inhibiting the P2Y12 ADP receptor on platelets has been proven to prevent thrombosis and subsequent heart attacks. Because of its properties, elinogrel has the potential to provide significant clinical advantages compared to Plavix(R)* (clopidogrel), the current standard of care; newer agents, such as prasugrel; and those in development, by lowering the risk of ischemic events due to clot formation and reducing the risk of bleeding. In addition, elinogrel is the only compound in development that can be administered intravenously in the hospital and orally in the chronic setting.
Portola also has proprietary pipeline programs focused on the discovery and development of novel, specific Syk and JAK inhibitors to treat cancer and inflammatory diseases; a thromboxane receptor antagonist, which is an aspirin replacement product for patients intolerant to aspirin; and a novel anticoagulant antidote program with the potential to help manage or reverse the bleeding complications in the tens of millions of patients expected to be treated with anticoagulants worldwide in the next decade. For additional information, visit www.portola.com.
SOURCE Portola Pharmaceuticals, Inc.
CONTACT: Mardi Dier, CFO of Portola Pharmaceuticals, +1-650-246-7236; or
Jani Bergan of Invigorate Communications, +1-415-946-1064, for Portola
Pharmaceuticals, Inc.
Web site: http://www.portola.com./
