Patheon Inc. (TSX: PTI) today announced that based on a preliminary review of 2006 results for the first quarter ended January 31, 2006, it expects that the previously disclosed difficulties with Omnicef(R) production at its Carolina, Puerto Rico facility will impact earnings by approximately 6 cents per share in the first quarter, not 3 cents per share as anticipated when the Company reported 2005 year end results in December 2005.