OXIS International, Inc. Antioxidant Compound L-ergothioneine Increases Sperm Cell Viability by 15-20% in Pre-Clinical and Clinical Studies

MONTVALE, N.J.--(BUSINESS WIRE)--Oxis International Inc. (OTCBB: OXIS) announced today that its lead antioxidant compound L-ergothioneine (ERGO) showed dramatic results in preserving function of sperm cells undergoing freezing and thawing. These experiments were designed by an expert in equine fertility, Lisa Metcalf, MS DVM Diplomate, American College of Theriogenology and executed in independent animal fertility laboratories. ERGO increased sperm cell viability by 15-20% in pre-clinical and clinical studies as measured by total and progressive motility, when added to known cell extender preservatives in general use in the fertility field. Percentage increases of this magnitude are significant considering the large numbers of cells involved.
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