Oragenics, Inc. Director George Hawes Resigns

ALACHUA, FL -- (MARKET WIRE) -- May 01, 2007 -- Oragenics, Inc. (AMEX: ONI) today announced that George Hawes is leaving his position as a member of the Board, effective immediately. Mr. Hawes has served as a Director since December 2005 and has resigned for personal reasons. Oragenics will initiate a search to locate a suitable candidate to fill this vacancy on the Board of Directors. “On behalf of Oragenics Board and the entire management team, I wish to thank George for his dedication and efforts to help build the Company,” said Robert T. Zahradnik, president and chief executive officer of Oragenics, Inc.

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