Nuvelo, Inc. Announces Upcoming Conference Calls, Webcasts And Conference Participation

SAN CARLOS, Calif., March 29 /PRNewswire-FirstCall/ -- Nuvelo, Inc. today announced that it will hold the following events in April:

CIBC World Markets Annual Biotechnology & Specialty Pharmaceuticals Conference April 5, 2006 1:45 p.m. ET Dr. Michael Levy, SVP Research & Development http://www.veracast.com/webcasts/cibcwm/biotech06/06210269.cfm

A live audio webcast of the presentation will also be available online via the Investor Relations portion of Nuvelo's website at www.nuvelo.com.

About Nuvelo

Nuvelo, Inc. is dedicated to improving the lives of patients through the discovery, development and commercialization of novel drugs for acute cardiovascular and cancer therapy. Nuvelo's development pipeline includes three acute cardiovascular programs focused on alfimeprase, a direct-acting thrombolytic in Phase 3 clinical trials for the treatment of thrombotic-related disorders; rNAPc2, an anticoagulant that inhibits the factor VIIa and tissue factor protease complex that is currently in Phase 2 clinical development for acute coronary syndromes and a thrombin inhibiting aptamer for anticoagulation during medical procedures. Nuvelo is also progressing an emerging oncology pipeline which includes NU206, for the potential treatment of chemotherapy/radiation therapy-induced mucositis, as well as rNAPc2 for potential use as a cancer therapy. In addition, Nuvelo expects to leverage its expertise in secreted proteins and cancer antibody discovery to further expand its pipeline and create additional partnering and licensing opportunities.

Information about Nuvelo is available at our website at www.nuvelo.com or by phoning 650-517-8000.

Nuvelo, Inc.

CONTACT: Nicole Estrin, Associate Director of Corporate Communications &IR of Nuvelo, Inc., +1-650-517-8472, or nestrin@nuvelo.com

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