Certain gene variants linked to prostate cancer may make men more susceptible to lower urinary tract symptoms, according to a new study. On the other hand, a different gene variant might protect against those symptoms, the study found. Researchers from the Feinberg School of Medicine at Northwestern University in Chicago identified 38 genetic sequence variants linked to prostate cancer risk in nearly 2,000 healthy, white men enrolled in a prostate cancer screening study. The men completed questionnaires on the severity of their lower urinary tract symptoms, their age and whether they took medications used to treat enlarged prostate (benign prostatic hyperplasia).