New Method Of Screening Children For Autism Spectrum Disorders Works At 9 Months Old
Washington, DC – Researchers, including a team from Children’s National Health System, have identified head circumference and head tilting reflex as two reliable biomarkers in the identification of autism spectrum disorders (ASD) in children that are between 9 and 12 months of age.
According to the U.S. Centers for Disease Control and Prevention, ASD is identifiable as early as two years old, although most children are not identified until after the age of four. While a number of studies have reported that parents of children with ASD notice developmental problems in children before their first birthday, there has yet to be a screening tool to identify those children.
“While the ‘gold standard’ screening tool is the M-CHAT questionnaire, it must be read and completed by parents and then interpreted by a health care provider,” said lead author Carole A. Samango-Sprouse, EdD, and Associate Clinical Professor of Pediatrics at the George Washington University School of Medicine and Health Sciences. “What physicians are missing is a quick and effective screening measure that can easily be given to all infants regardless of background and identify ASD before 12 months. This screening is also helpful in identifying those babies who may not initially appear to be at risk and would otherwise be missed until much later in life.”
This study looked at the use of head circumference and head tilting reflex as two biomarkers that can be used during their well-baby visits by their primary care providers. Both screenings were given to nearly 1,000 patients at the four, six, and nine-month well-baby visits.
At the end of nine months, those infants with a head circumference above or equal to the 75th percentile, a head circumference that was in 10 percent discrepancy with the height of the baby, or those who failed the head tilting reflex test were considered at risk for ASD or a developmental language delay. These infants were then evaluated by a neurodevelomental specialist and pediatric neurologist to differentiate between these disorders.
Of the 49 infants that displayed abnormal results, without previous diagnosis, 15 were identified at risk for ASD and 34 at risk for developmental language delay. Of the 15 children who were identified at risk for ASD between 9 and 12 months of age, 14 (93 percent) sustained the diagnosis when it was made clinically at the age of three.
“We will continue looking at the efficacy of the head circumference and head tilting reflex as a screening tool for these disorders,” said Andrea Gropman, MD, a contributor to the study and Division Chief of Neurogenetics at Children’s National. “As with all developmental delays, especially ASD, the sooner we can identify those children who are at risk, the sooner we can intervene and provide appropriate treatment. In other words, the sooner we identify these delays, the better the outcome for those affected.”
###
Contact: Emily Hartman or Caitlyn Camacho at 202-476-4500.
Related Links
Center for Autism Spectrum Disorders at Children’s National
Genetics program at Children’s National
About Children’s National Health System
Children’s National Health System, based in Washington, DC, has been serving the nation’s children since 1870. Children’s National’s hospital is Magnet® designated, and is consistently ranked among the top pediatric hospitals by U.S.News & World Report. Home to the Children’s Research Institute and the Sheikh Zayed Institute for Pediatric Surgical Innovation, Children’s National is one of the nation’s top NIH-funded pediatric institutions. With a community-based pediatric network, eight regional outpatient centers, an ambulatory surgery center, two emergency rooms, an acute care hospital, and collaborations throughout the region, Children’s National is recognized for its expertise and innovation in pediatric care and as an advocate for all children. For more information, visit ChildrensNational.org, or follow us on Facebook and Twitter.
Hey, check out all the engineering jobs. Post your resume today!
