Medivir AB (MVIRB)’s experimental hepatitis C treatment TMC435 cured as many as 80 percent of patients 24 weeks after treatment ended, suggesting that the therapy prevents the virus from surging back.
The mid-stage Aspire trial looked at the medicine in combination with the current standard of care of interferon and ribavirin. The virus was cleared 24 weeks after treatment ended in 80 percent of patients who took a once daily TMC435 dose of 150 milligrams for 48 weeks. The sustained cure rate was 70 percent among patients who took 100 milligrams of the drug for 12 weeks. The results were announced today at a medical meeting in Barcelona.
The mid-stage Aspire trial looked at the medicine in combination with the current standard of care of interferon and ribavirin. The virus was cleared 24 weeks after treatment ended in 80 percent of patients who took a once daily TMC435 dose of 150 milligrams for 48 weeks. The sustained cure rate was 70 percent among patients who took 100 milligrams of the drug for 12 weeks. The results were announced today at a medical meeting in Barcelona.
