Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Prognosis of patients with HCC complicating cirrhosis mainly depends on the tumor growth, progression of the underlying liver disease and the effectiveness of antitumoral treatment. Trans-catheter treatment is extensively used to treat HCC not suitable for surgical resection or percutaneous ablation therapies. Unfortunately, the tumor response after trans-catheter treatment is heterogeneous, with a wide range of necrosis that cannot be accurately predicted.
