CAMBRIDGE, Mass.--(BUSINESS WIRE)--Knome, a life sciences company that interprets human genomes to identify the genetic factors that influence disease risk, today announced that its services aided in the discovery of a mutation associated with an inherited form of Parkinson’s disease (PD). The research, led by investigators from the University of British Columbia (UBC), leveraged recent advances in human exome sequencing and bioinformatics analysis to identify a mutation in vacuolar protein-sorting associated protein 35 (VPS35) as a genetic determinant of late-onset PD. Their findings were published online on July 14 and in the July 15 issue of the American Journal of Human Genetics.
