New Scientist -- WILL swine flu virus turn nasty as the northern hemisphere winter gets under way? All previous pandemic flu strains started off mild before becoming deadlier, so health authorities are taking the threat seriously. They know that if 2009 H1N1 flu does become more lethal over the next few months, we will be nearly defenceless: there are already signs of resistance to Tamiflu, and any vaccines will be in very short supply.