Scientists from the Freie Universität Berlin have identified mechanisms regulating chemical neurotransmission in the nervous system. Scientists from the Freie Universität Berlin and the NeuroCure Cluster of Excellence, led by Volker Haucke in collaboration with colleagues from the Leibniz Institute for Molecular Pharmacology (FMP) in Berlin, have unravelled a mechanism involved in the reformation of neurotransmitter containing membrane vesicles in the brain. Perturbations of this reformation process, because of mutations in key proteins such as CALM and AP180, are a possible cause for the development of neurodegenerative disorders such as Alzheimer’s disease.
