Gene Therapy Technique: Water Droplets Produced By Electrospray Render Cells Permeable To External DNA

Genetically engineered products have become indispensable. For example, genetically modified bacteria produce human insulin. In future, gene therapy should make it possible to introduce genes into the cells of a diseased organism so that they can address deficiencies to compensate for malfunctions in the body. In order for this to work, foreign (or synthetic) DNA must be introduced into host cells, which is not exactly a trivial task. Japanese researchers have now developed a method which could represent a true alternative to conventional processes. The cells are “bombarded” with water droplets produced and accelerated by electrospray.

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