Gene Test Could Spot Dangerous Heart Condition

Researchers say they’ve developed a new gene-based test for long QT syndrome (LQTS), a heart condition that can predispose people to cardiac arrhythmias and sudden death.A team from the S. Maugeri Foundation, in Pavia, Italy, conducted genetic testing on 430 LQTS patients and 1,115 of their family members, looking for mutations linked to the disorder.They identified 235 different mutations -- including 138 new ones -- in 310 (72 percent) of the 430 patients. The team confirmed its findings by testing for the mutations in a separate group of 75 LQTS patients.The findings appear in the Dec. 21 issue of the Journal of the American Medical Association.

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