SAN FRANCISCO--(BUSINESS WIRE)--FibroGen, Inc. today announced initiation of a phase 2 study to compare the efficacy of FG-3019, a human monoclonal antibody against connective tissue growth factor (CTGF), with placebo in reversing liver fibrosis (scarring of the liver) due to chronic infection with hepatitis B virus (HBV). FG-3019 will be studied on a background of the antiviral therapy entecavir. The study is being conducted in Hong Kong where approximately 10% of the population has chronic HBV and is consequently at increased risk of progression to liver failure and hepatocellular carcinoma (HCC).
