The single unit will feature a breakable wall between the two chambers for rapid mixing. This reconstituted plasma would be administered intravenously to restore the normal blood clotting ability of a severely wounded patient. The prototype will be constructed of a unique flexible and durable plastic, to support the storage of dried plasma powder at extreme temperatures. The Department of the Navy contract requires that Entegrion complete this prototype within six months.
“Entegrion is honored by the Navy’s confidence in our experience toward improving the stability and availability of blood and blood components, wherever they are needed,” according to Stan Eskridge, Entegrion's president and CEO.
Resusix, concentrated human plasma that is spray dried for long-term storage, is currently in development at Entegrion. Clinical trials will begin in the late 2009 and spray dried plasma for civilian application is expected by 2012.
About Entegrion
Entegrion is a life sciences company that selectively integrates synergistic technologies with those in its patent portfolio for development of novel devices and drugs for hemorrhage control, resuscitation and associated tissue repair. The company is based in North Carolina’s Research Triangle Park, and is the inventor of Stasilon™ – the hemostatic medical textile technology cleared by the FDA for use by prescription and also by consumers – from which multiple hemorrhage control products are being made.
Building upon technologies licensed from the University of North Carolina, Entegrion’s portfolio includes platelet-derived platform technologies that are being developed as topical gels and sprays for tissue repair, infusible hemostatic agents for the control of internal hemorrhage, and novel vehicles for delivery of drugs to targeted tumors and other sites of internal bleeding. Entegrion has also developed proprietary techniques for drying plasma and other blood components to provide for long shelf life with rapid rehydration for emergent and clinical use. For more information, visit www.entegrion.com.
