ST. PAUL, Minn. – A popular epilepsy drug taken by pregnant women with epilepsy because of its mild risk of birth defects has been linked to increased seizure activity in up to 75 percent of pregnancies. Now, new research shows that monitoring the level of the drug in the blood helps to reduce the increased seizure activity associated with the drug lamotrigine and improve the overall health of pregnant women and their fetuses. The findings are published November 28, 2007, in the online edition of Neurology®, the medical journal of the American Academy of Neurology.