Detecting Cold, Feeling Pain: University of California, San Francisco (UCSF) Study Reveals Why Menthol Feels Fresh

Scientists have identified the receptor in cells of the peripheral nervous system that is most responsible for the body’s ability to sense cold.The finding, reported on-line in the journal “Nature” (May 30, 2007), reveals one of the key mechanisms by which the body detects temperature sensation. But in so doing it also illuminates a mechanism that mediates how the body experiences intense stimuli – temperature, in this case – that can cause pain.

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