Celgene Corp has warned doctors in the UK that its newly approved blood cancer drug Imnovid can cause life-threatening birth defects. In a letter to healthcare professionals, the drugmaker stressed that the medicine is structurally related to thalidomide, a known human teratogen that causes severe life-threatening birth defects. Because of a similar effect observed in rabbits and rats, taking Imnovid (pomalidomide) during pregnancy is also expected to have a tetratogenic effect in humans, it said.
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