ALAMEDA, Calif.--(BUSINESS WIRE)--BioTime, Inc. (NYSE Amex:BTX) announced today the publication in the peer-reviewed journal Stem Cell Research of the complete genome sequence analysis of five clinical-grade human embryonic stem cell lines. “Evaluating the Genomic and Sequence Integrity of Human ES Cell Lines: Comparison to Normal Genomes” is the first such analysis of the entire genome of human embryonic stem cell lines and further establishes BioTime’s lead in developing fully characterized cell lines intended for use in the manufacture of therapeutics. The report documents aspects of the sequences of BioTime’s ESI embryonic stem cell lines, analyzes several key features that can affect transplantation (blood type, telomere length, and tissue compatibility), and details methods to ensure the genomic and genetic integrity of these lines and products derived from them. The paper includes co-authors from Complete Genomics, Inc., which collaborated in the whole genome sequencing for the project, and Cell Line Genetics, Inc., a full-service company providing cytogenetic testing. The publication is available online as an accepted article in press in the journal Stem Cell Research.
