IRVINE, CA and LAUSANNE, Switzerland, Dec. 15 /CNW/ - IsoTis SA ("IsoTis"
or the "Company") and its wholly-owned U.S. subsidiary, IsoTis, Inc., jointly
announce that the exchange offer by IsoTis, Inc. to all shareholders of IsoTis
to exchange their current IsoTis shares for shares of IsoTis, Inc. (the
"Exchange Offer") commences today and is expected to end on January 19, 2007.