“The successful identification and structure elucidation of active ligands to a previously orphan receptor within the initial OLNORME collaboration with Genfit was based on the screening of ProfilesTM from BICOLL’s highly diversified library of plant metabolites.”, declared Dr. Kai Lamottke, Managing Director of BICOLL. “With our expertise in natural product chemistry and medicinal chemistry, we were able to contribute significantly to our partner’s progress in internal research programs.”
In the successive OLNORME II program the consortium will now develop new drug development candidates with great potential to treat cardio metabolic and neurodegenerative diseases including atherosclerosis, type 2 diabetes, obesity and Alzheimer disease. BICOLL will contribute with its expertise in medicinal chemistry to the hit to lead optimization phase. BICOLL will as well evaluate structural and functional diversity of hit compound families and additionally support Genfit during lead compound characterization and preclinical development. As third partner for the European joint research project OLNORME II, University of Freiburg, research group of Professor Dr. Peter Spiteller was selected as academic partner.
About BICOLL:
BICOLL is a biopharmaceutical company, offering pre-clinical support in the area of Drug Discovery from Natural Products and Medicinal Chemistry. Dedicated to the discovery and optimization of the highest quality lead compounds, BICOLL provides an efficient, multi-disciplinary approach to drug discovery. With outstanding expertise in high tech natural product chemistry and validated experience in medicinal chemistry, BICOLL increases quality and quantity of the drug discovery pipeline of its partner's candidates portfolio.
The BICOLL Group provides its services to a number of international clients of various fields of interest, e.g. pharmaceutical and agrochemical industry. The BICOLL Group comprises two legal entities: BICOLL GmbH in Munich, Germany and BICOLL Biotechnology (Shanghai) Co. Ltd., P.R. China. Technology development, cooperation management and marketing are functions in Munich, while facilities for research and development are located in Shanghai. BICOLL currently employs 40 people at both locations.
For further information please contact:
Dr. Nicole Feling
Public Relations Management
Tel: +49 (0) 89 / 82010630,
nicole.feling@bicoll-group.com