Aspirin’s Heart Benefits Varies By Sex

The battle of the sexes may even extend to aspirin: A new “study of studies” finds the cardio-protective drug benefits men very differently than it does women.The review of six studies, involving more than 95,000 people, showed that aspirin therapy cut the incidence of stroke in women but not men.On the other hand, when it came to heart attack the reverse was true: Daily use of aspirin reduced the incidence of those events in men but not women."Nobody has any ideas about the cause of the difference,” said study senior author Dr. David L. Brown, chief of cardiology at the State University of New York at Stony Brook. “It needs to be an important research priority for the future."He believes future research on the issue should center on factors such as how men and women “metabolize aspirin, and how it acts on blood platelets [cells] and blood vessels."The report appears in the Jan. 18 issue of the Journal of the American Medical Association.

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