PhaseBio Pharmaceuticals, Inc. Launches Clinical Program to Evaluate Novel VPAC2 Agonist for Cardiovascular Disease

MALVERN, Pa.--(BUSINESS WIRE)--PhaseBio Pharmaceuticals, Inc., a privately held, clinical-stage biotechnology company developing drugs to treat diabetes, metabolic disease and cardiovascular disease, announced today that it has begun dosing subjects in a Phase 1 clinical study with its novel compound, VasomeraTM (PB1046), in patients with Stage 1 and 2 essential hypertension. VasomeraTM is a VPAC2-selective Vasoactive Intestinal Peptide (VIP) agonist which has been genetically engineered using the company’s elastin-like biopolymer (ELP) technology to provide a long-acting, slow adsorption product profile that is being developed as an adjunctive therapy for the treatment of hypertension as well as for congestive heart failure, a common complication of chronically elevated blood pressure.