Pain Therapeutics To Host Conference Call Today, Monday, December 12, 2005 9:00 A.M. Eastern Time

SOUTH SAN FRANCISCO, Calif., Dec. 12 /PRNewswire-FirstCall/ -- Pain Therapeutics, Inc. , a biopharmaceutical company, today announced that management will host a conference call today at 9:00 a.m. EST/6:00 a.m. Pacific Time to briefly discuss its perspective on 2006.

To participate in the conference call, please dial 866-831-6267 (within the U.S.) or 617-213-8857 (outside the U.S.) fifteen minutes prior to the start of the call. The call reference number is 33968178. A playback of the conference call will be available following the live event. To access the playback, please dial 888-286-8010 (within the U.S.) or 617-801-6888 (outside the U.S.) and enter reservation number 66816316.

A webcast of the conference call will also be available online at

About Pain Therapeutics, Inc.

We are a biopharmaceutical company that develops novel drugs. We have two lead drug candidates in late-stage clinical trials, Remoxy(TM) and Oxytrex(TM). Both drugs are in Phase III programs and are aimed at different segments of the multi-billion dollar market to treat severe chronic pain, such as low-back pain or pain due to osteoarthritis.

Pain Therapeutics, Inc.

CONTACT: Christi Waarich, Senior Manager of Investor Relations of PainTherapeutics, Inc., +1-650-825-3324, or; or media,Carney Duntsch of Burns McClellan +1-212-213-0006, for Pain Therapeutics

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