Linnaeus Therapeutics Awarded $4,000,000 SBIR Phase 2 Bridge Award by the National Cancer Institute to Advance LNS8801 for the Treatment of Cutaneous and Uveal Melanoma
HADDONFIELD, N.J., April 6, 2022 /PRNewswire/ -- Linnaeus Therapeutics, Inc. ("Linnaeus"), a privately held biopharmaceutical company focused on the development and commercialization of novel small molecule oncology therapeutics, today announced it has been awarded a Phase 2 Bridge Small Business Innovation Research ("SBIR") Award by the National Cancer Institute ("NCI") of the National Institutes of Health ("NIH").
The $4,000,000 award was granted to the company after a highly competitive peer-review process. The award will help fund the clinical development of its lead compound, LNS8801, which targets a G protein-coupled receptor (GPER), for the treatment of metastatic cutaneous and uveal melanoma both as a monotherapy and in combination with pembrolizumab.
"This award provides a strong peer-reviewed validation of the core science that is the basis of LNS8801, its target GPER, and the early clinical data seen in patients with cancer," said Patrick Mooney, MD, Chief Executive Officer of Linnaeus. "This award will allow us to further advance LNS8801 as a potentially safe and effective oral therapeutic for the treatment of metastatic cutaneous and uveal melanoma. We thank the NCI for their ongoing support and belief in the potential of LNS8801 to help patients with cancer."
In the ongoing clinical study in humans, LNS8801 monotherapy has been safe and well tolerated. Additionally, LNS8801 has demonstrated target engagement, c-Myc protein depletion, and clinical benefit in patients with advanced cancer.
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SOURCE Linnaeus Therapeutics, Inc.