Editas Medicine to Present Preclinical Data Demonstrating Advancements in In Vivo Gene Editing Approach for the Treatment of Genetic Ocular Diseases at the Association for Research in Vision and Ophthalmology Annual Meeting
Preclinical data support novel approaches for the treatment of Usher Syndrome 2A and retinitis pigmentosa 4
CAMBRIDGE, Mass., May 01, 2021 (GLOBE NEWSWIRE) -- Editas Medicine, Inc. (Nasdaq: EDIT), a leading genome editing company, today announced that two scientific abstracts have been accepted for presentation at the Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting being held virtually May 1 – 7, 2021. The Company is presenting preclinical data on its Usher Syndrome 2A (USH2A) and retinitis pigmentosa 4 (RP4) programs.
Editas Medicine’s presentations at ARVO will include preclinical data demonstrating:
- Gene edited USH2A exon 13 deletion restored USH2 protein complex expression and rescued deficits in photoreceptor morphology in human retinal organoids; and
- Clinically relevant levels of editing using a dual AAV CRISPR-Cas9 system as a therapeutic strategy for the treatment of RP4.
“Editas Medicine is making significant advancements in our efforts to treat ocular diseases, and we look forward to sharing recent progress and preclinical data on our USH2A and RP4 programs this week at the ARVO Annual Meeting,” said Kate Zhang, Vice President, Biological Development, Editas Medicine. “This data further supports our advancing these programs towards the clinic and our belief in the potential for gene editing medicines to transform the lives of those living with inherited retinal diseases.”
The complete list of Editas Medicine presentations is below. Abstracts can be accessed on the ARVO website at https://arvo2021.arvo.org/abstracts.
CRISPR Gene Editing Rescues Deficits in Human USH2A Mutant Retinal Organoids
Date/Time: Tuesday, May 4, 2021, 2:15 p.m. – 3:45 p.m. EDT
Session: Gene Therapy in Ocular Diseases
Advances Towards a Dual AAV CRISPR-Cas9-based ‘Knockout and Replace’ Strategy to Treat Rhodopsin-associated Autosomal Dominant Retinitis Pigmentosa
Date/Time: Monday, May 3, 2021, 11:15 a.m. – 1:00 p.m. EDT
Session: Gene Editing and Ocular Therapies
About Editas Medicine
As a leading genome editing company, Editas Medicine is focused on translating the power and potential of the CRISPR/Cas9 and CRISPR/Cas12a (also known as Cpf1) genome editing systems into a robust pipeline of treatments for people living with serious diseases around the world. Editas Medicine aims to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for a broad class of diseases. For the latest information and scientific presentations, please visit www.editasmedicine.com.
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