Beckman Coulter, Inc. Release: New Cell Signaling Reagents Measure Responses to Cell Stimuli

Fullerton, Calif. (April 30, 2007) – Beckman Coulter, Inc. introduces two additions to its line of cell signal transduction reagents – Phospho-MAPKAPK-2 and Phospho-STAT3 kinase antibodies. These single-color flow cytometric reagents measure kinase activation in the cytoplasm and are valuable for cell function research. By measuring the phosphorylation of specific intracellular proteins, these RUO reagents can aid in the study of surface-to-nucleus cell signal transduction pathways. The Phospho-MAPKAPK2 marker is particularly useful in the study of pro-inflammatory mediator release, actin reorganization and cell invasion mechanisms. The Phospho-STAT3 marker that translocates to the cell nucleus upon activation plays a key role in many cellular processes such as cell growth and apoptosis.