Applied Nanoscience Invited to Present at the Department of Health and Human Services on NanoFense(TM) Formulation

CARLSBAD, CA--(Marketwire - March 18, 2009) -

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Applied Nanoscience Inc. (ANI) (PINKSHEETS: APNN), a nanotechnology-based filtration development company, today announced that it has accepted an invitation from the U.S. Department of Health and Human Services to present on its core technology, NanoFense™, a proprietary antimicrobial nanoparticle formulation developed by ANI to coat or impregnate virtually any air filter media. The material presented will specifically focus on protective and surgical mask applications and comprehensively cover the company's successful independent testing against avian influenza and other harmful pathogens.

"We are excited and flattered to have this opportunity in sharing our continued technology developments with such an important organization. DHHS is certainly qualified to offer constructive advice on ANI's primary objective of proactively protecting people from harmful disease," said Thomas K. Allen, President and CEO, ANI. "In addition, we hope to progress in making the technology widely available to consumers with the guidance provided at the meeting."

About ANI

ANI is a marketer and developer of innovative, high performance nanotechnology-based filtration products to customers worldwide and is the owner of NEFT™ (Nanoparticle - Enhanced - Filtration - Technology), a broad platform with significant application potential in consumer market segments.

For further information about Applied Nanoscience Inc., please visit: www.appliednanoscience.com

Safe Harbor Statement

This release may contain statements that are forward-looking. Such statements are made based upon current expectations that are subject to risk and uncertainty. ANI does not undertake to update forward-looking statements in this news release to reflect actual results of and changes in assumptions or changes in other factors affecting such forward-looking information. The actual future plans and results of the company could differ significantly from such forward-looking statements.